- Ed Boyden, PhD, MIT Media lab
- Edward Chang, MD, University of California, San Francisco
- Valentina Greco, PhD, Yale University
- Jayaraj Rajagopal, MD, Massachusetts General Hospital
- Marius Wernig, MD, PhD, Stanford University
- Feng Zhang, PhD, Broad Institute of MIT and Harvard
Each year, NYSCF University, our ten-week summer internship program, gives top college students from around the world the opportunity to work in the NYSCF Research Institute laboratories with NYSCF scientists and engineers. This video features the students in the 2016 NYSCF University class sharing what this experience has meant to them in their own words.
NYSCF – Druckenmiller Fellow Dr. Hongda Li, The Rockefeller University, was first author on two papers investigating the zika virus. The first paper, published in Cell Stem Cell, described how zika may affect adult brain cells in addition to the mounting evidence that it causes abnormalities in the brains of developing fetuses. Using adult mouse models, the scientists showed that zika infects neural progenitor cells, cells thought to be critical in learning and memory.
The second paper in The American Journal of Human Genetics identified genetic mutations linked to the mechanisms causing autosomal-recessive primary microcephaly, a genetic form of microencephaly. This research helps illuminate the specific genetic pathways leading to microencephaly, a devastating side effect of zika infection in utero.
NYSCF – Robertson Investigator Alumna Dr. Shuibing Chen published her latest work in Cell Stem Cell creating stem cell models of type 2 diabetes in a step towards applying knowledge from genome-wide association studies to drug discovery efforts. Dr. Chen and her team at Weill Cornell Medical College created human stem cell models with genetic mutations in genes associated with the development of type 2 diabetes as identified through genome-wide association studies.
These stem cell models allow scientists to further interrogate the genes in question without harming patients, paving the way for precision therapy for metabolic diseases including type 2 diabetes.